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LZTS1 Antibody (CF810241) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LZTS1 (RC210424, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-LZTS1. Positive lysates LY412145 (100 µg) and LC412145 (20 µg) can be purchased separately from OriGene.
Product Details
CF810241
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI3D12
Immunogen
Full length human recombinant protein of human LZTS1 produced in HEK293T Cell.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: F37 esophageal cancer-related leucine zipper motif 1; F37/Esophageal cancer-related gene-coding leucine-zipper motif; Fez1; Leucine zipper putative tumor suppressor 1; leucine zipper, putative tumor suppressor 1; leucine-zipper protein FEZ1; PSD-Zip70
Gene Aliases: F37; FEZ1; LZTS1; Psdzip70
UniProt ID: (Human) Q9Y250, (Mouse) P60853, (Rat) Q8CFC9
Entrez Gene ID: (Human) 11178, (Mouse) 211134, (Rat) 266711
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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