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LASS2 is a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. This gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described.
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Protein Aliases: Ceramide synthase 2; CerS2; FLJ10243; LAG1 homolog, ceramide synthase 2; LAG1 longevity assurance 2; LAG1 longevity assurance homolog 2; longevity assurance (LAG1, S. cerevisiae) homolog 2; MGC987; SP260; Sphingosine N-acyltransferase CERS2; Tumor metastasis-suppressor gene 1 protein; Very-long-chain ceramide synthase CERS2
Gene Aliases: CERS2; L3; LASS2; SP260; TMSG1
UniProt ID: (Human) Q96G23
Entrez Gene ID: (Human) 29956
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