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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide, corresponding to amino acids 51-68 (SPVKRPGRKAARVLGSEG) of Human Lig1.|
|Storage buffer||PBS with 0.1mg/ml BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-29815 detects Ligase 1 from human samples.
PA1-29815 has been successfully used in Western blot applications.
The PA1-29815 immunogen is: Synthetic peptide, corresponding to amino acids 51-68 (SPVKRPGRKAARVLGSEG) of Human Lig1.
LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ligase I, DNA, ATP-dependent; MGC117397; MGC130025; polydeoxyribonucleotide synthase [ATP] 1