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FIGURE: 1 / 3
Positive control: Human tonsil tissue, human diffuse large B-cell lymphoma tissue, Daudi.
Predicted band size: 29 kDa
Subcellular Location: Cell membrane, Endoplasmic reticulum membrane, Golgi apparatus, Endosome membrane, Lysosome membrane.
The human MHC class II is encoded by three different isotypes, HLA-DR, -DQ, and -DP, all are highly polymorphic. HLA-DP molecules have not been studied extensively. HLA-DP is a protein complex found on the surface of antigen-presenting cells, such as dendritic cells, macrophages, and B cells. Its main function is to present peptides derived from extracellular proteins to CD4+ T cells for immune recognition.
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: beta1 domain MHC class II HLA DPB; class II HLA beta chain; HLA class II histocompatibility antigen, DP beta 1 chain; HLA class II histocompatibility antigen, DP(W4) beta chain; HLA DP14-beta chain; HLA-DP histocompatibility type, beta-1 subunit; major histocompatibility complex class II antigen beta chain; MHC class II antigen beta chain; MHC class II antigen DP beta 1 chain; MHC class II antigen DPB1; MHC class II antigen DPbeta1; MHC class II HLA-DP-beta-1; MHC class II HLA-DRB1; MHC HLA DPB1
Gene Aliases: DPB1; HLA-DP; HLA-DP1B; HLA-DPB; HLA-DPB1
UniProt ID: (Human) Q5EP52
Entrez Gene ID: (Human) 3115
Molecular Function: major histocompatibility complex protein
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