|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to the N-terminal residues of human MAP1LC3 C. The sequence is 100% conserved in in Macaca mulatta (monkey) and canine|
|Storage buffer||whole serum|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:100|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-18286 detects MAP1LC3 C from human samples.
PA1-18286 has been successfully used in immunohistochemistry, immunofluorescence, and Western blot procedures.
The PA1-18286 immunogen is a synthetic peptide corresponding to the N-terminal residues of human MAP1LC3 C, conjugated to Blue Carrier Protein. The sequence is 100% conserved in in Macaca mulatta (monkey) and canine.
Reconstitute with 100 ul of distilled water.
Autophagy is a highly regulated bulk degradation process that plays an important role in cellular maintenance and development. MAP1LC3C is 1 of 3 orthologs of the yeast autophagosome protein Atg8 (He et al., 2003 [PubMed 12740394]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.