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MIG6/ERRFI1 Polyclonal Antibody

MIG6/ERRFI1 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 11

MIG6/ERRFI1 Antibody (11630-1-AP) in ICC/IF

Immunofluorescent analysis of PC-3 cells using 11630-1-AP (MIG6; ERRFI1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

MIG6/ERRFI1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

MIG6/ERRFI1 Antibody in Western Blot (WB)

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Product Details

11630-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 11 publications 11 publications

Immunohistochemistry (IHC)

View 7 publications 7 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:20-1:200

View 3 publications 3 publications

Immunoprecipitation (IP)

View 1 publication 1 publication

Miscellaneous PubMed (Misc)

View 1 publication 1 publication

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

MIG6; ERRFI1 Fusion Protein Ag2202 (113-462 aa encoded by BC025337)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.27 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: CGFKKLTVN GVCASTPPLT PIKNSPSLFP CAPLCERGSR PLPPLPISEA LSLDDTDCEV EFLTSSDTDF LLEDSTLSDF KYDVPGRRSF RGCGQINYAY FDTPAVSAAD LSYVSDQNGG VPDPNPPPPQ THRRLRRSHS GPAGSFNKPA IRISNCCIHR ASPNSDEDKP EVPPRVPIPP RPVKPDYRRW SAEVTSSTYS DEDRPPKVPP REPLSPSNSR TPSPKSLPSY LNGVMPPTQS FAPDPKYVSS KALQRQNSEG SASKVPCILP IIENGKKVSS THYYLLPERP PYLDKYEKFF REAEETNGGA QIQPLPADCG ISSATEKPDS KTKMDLGGHV KRKHLSYVVS P (113-462 aa encoded by BC025337)

Target Information

ERRFI1 is a cytoplasmic protein whose expression is upregulated with cell growth (Wick et al., 1995). It shares significant homology with the protein product of rat gene-33, which is induced during cell stress and mediates cell signaling (Makkinje et al., 2000).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Hexachlorophene, a selective SHP2 inhibitor, suppresses proliferation and metastasis of KRAS-mutant NSCLC cells by inhibiting RAS/MEK/ERK and PI3K/AKT signaling pathways.

Toxicology and applied pharmacology

Fu NJ,Xi RY,Shi XK,Li RZ,Zhang ZH,Li LY,Zhang GL,Wang F

Fri Apr 15 00:00:00 UTC 2022

Androgen-Induced MIG6 Regulates Phosphorylation of Retinoblastoma Protein and AKT to Counteract Non-Genomic AR Signaling in Prostate Cancer Cells.

Biomolecules

Schomann T,Mirzakhani K,Kallenbach J,Lu J,Rasa SMM,Neri F,Baniahmad A

Fri Jul 29 00:00:00 UTC 2022

Androgen-Induced MIG6 Regulates Phosphorylation of Retinoblastoma Protein and AKT to Counteract Non-Genomic AR Signaling in Prostate Cancer Cells.

Biomolecules

Schomann T,Mirzakhani K,Kallenbach J,Lu J,Rasa SMM,Neri F,Baniahmad A

Fri Jul 29 00:00:00 UTC 2022

p52Shc regulates the sustainability of ERK activation in a RAF-independent manner.

Molecular biology of the cell

Yoshizawa R,Umeki N,Yamamoto A,Okada M,Murata M,Sako Y

Wed Sep 01 00:00:00 UTC 2021

MIG-6 is essential for promoting glucose metabolic reprogramming and tumor growth in triple-negative breast cancer.

EMBO reports

He J,Li CF,Lee HJ,Shin DH,Chern YJ,Pereira De Carvalho B,Chan CH

Wed May 05 00:00:00 UTC 2021

ERRFI1 induces apoptosis of hepatocellular carcinoma cells in response to tryptophan deficiency.

Cell death discovery

Cui M,Liu D,Xiong W,Wang Y,Mi J

Mon Oct 04 00:00:00 UTC 2021

ERRFI1 induces apoptosis of hepatocellular carcinoma cells in response to tryptophan deficiency.

Cell death discovery

Cui M,Liu D,Xiong W,Wang Y,Mi J

Mon Oct 04 00:00:00 UTC 2021

ERRFI1 induces apoptosis of hepatocellular carcinoma cells in response to tryptophan deficiency.

Cell death discovery

Cui M,Liu D,Xiong W,Wang Y,Mi J

Mon Oct 04 00:00:00 UTC 2021

ERRFI1 induces apoptosis of hepatocellular carcinoma cells in response to tryptophan deficiency.

Cell death discovery

Cui M,Liu D,Xiong W,Wang Y,Mi J

Mon Oct 04 00:00:00 UTC 2021

Altered Expression of Three EGFR Posttranslational Regulators MDGI, MIG6, and EIG121 in Invasive Breast Carcinomas.

Analytical cellular pathology (Amsterdam)

Meseure D,Drak Alsibai K,Vacher S,Hatem R,Nicolas A,Callens C,Lerebours F,Bieche I

Wed Jan 13 00:00:00 UTC 2021

AAV-Mig-6 Increase the Efficacy of TAE in VX2 Rabbit Model, Is Associated With JNK Mediated Autophagy.

Journal of Cancer

Li Z,Tian Y,Qu L,Mao J,Zhong H

Thu Oct 01 00:00:00 UTC 2020

AAV-Mig-6 Increase the Efficacy of TAE in VX2 Rabbit Model, Is Associated With JNK Mediated Autophagy.

Journal of Cancer

Li Z,Tian Y,Qu L,Mao J,Zhong H

Thu Oct 01 00:00:00 UTC 2020

AAV-Mig-6 Increase the Efficacy of TAE in VX2 Rabbit Model, Is Associated With JNK Mediated Autophagy.

Journal of Cancer

Li Z,Tian Y,Qu L,Mao J,Zhong H

Thu Oct 01 00:00:00 UTC 2020

CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.

The Journal of pathology

Ichise T,Yoshida N,Ichise H

Sun Sep 01 00:00:00 UTC 2019

Profiling of protein-protein interactions via single-molecule techniques predicts the dependence of cancers on growth-factor receptors.

Nature biomedical engineering

Lee HW,Choi B,Kang HN,Kim H,Min A,Cha M,Ryu JY,Park S,Sohn J,Shin K,Yun MR,Han JY,Shon MJ,Jeong C,Chung J,Lee SH,Im SA,Cho BC,Yoon TY

Sun Apr 01 00:00:00 UTC 2018

Mig-6 is down-regulated in HCC and inhibits the proliferation of HCC cells via the P-ERK/Cyclin D1 pathway.

Experimental and molecular pathology

Li Z,Qu L,Luo W,Tian Y,Zhai H,Xu K,Zhong H

Thu Jun 01 00:00:00 UTC 2017

Mig-6 is down-regulated in HCC and inhibits the proliferation of HCC cells via the P-ERK/Cyclin D1 pathway.

Experimental and molecular pathology

Li Z,Qu L,Luo W,Tian Y,Zhai H,Xu K,Zhong H

Thu Jun 01 00:00:00 UTC 2017

Mig-6 is down-regulated in HCC and inhibits the proliferation of HCC cells via the P-ERK/Cyclin D1 pathway.

Experimental and molecular pathology

Li Z,Qu L,Luo W,Tian Y,Zhai H,Xu K,Zhong H

Thu Jun 01 00:00:00 UTC 2017

Mig-6 is down-regulated in HCC and inhibits the proliferation of HCC cells via the P-ERK/Cyclin D1 pathway.

Experimental and molecular pathology

Li Z,Qu L,Luo W,Tian Y,Zhai H,Xu K,Zhong H

Thu Jun 01 00:00:00 UTC 2017

RNA-binding protein SAMD4 regulates skeleton development through translational inhibition of Mig6 expression.

Cell discovery

Niu N,Xiang JF,Yang Q,Wang L,Wei Z,Chen LL,Yang L,Zou W

Thu Oct 01 00:00:00 UTC 2020

RNA-binding protein SAMD4 regulates skeleton development through translational inhibition of Mig6 expression.

Cell discovery

Niu N,Xiang JF,Yang Q,Wang L,Wei Z,Chen LL,Yang L,Zou W

Thu Oct 01 00:00:00 UTC 2020

A genome landscape of SRSF3-regulated splicing events and gene expression in human osteosarcoma U2OS cells.

Nucleic acids research

Ajiro M,Jia R,Yang Y,Zhu J,Zheng ZM

Mon Feb 29 00:00:00 UTC 2016

A genome landscape of SRSF3-regulated splicing events and gene expression in human osteosarcoma U2OS cells.

Nucleic acids research

Ajiro M,Jia R,Yang Y,Zhu J,Zheng ZM

Mon Feb 29 00:00:00 UTC 2016

Mitogen-inducible gene-6 partly mediates the inhibitory effects of prenatal dexamethasone exposure on endochondral ossification in long bones of fetal rats.

British journal of pharmacology

Zhang X,Shang-Guan Y,Ma J,Hu H,Wang L,Magdalou J,Chen L,Wang H

Fri Jul 01 00:00:00 UTC 2016

Mitogen-inducible gene-6 partly mediates the inhibitory effects of prenatal dexamethasone exposure on endochondral ossification in long bones of fetal rats.

British journal of pharmacology

Zhang X,Shang-Guan Y,Ma J,Hu H,Wang L,Magdalou J,Chen L,Wang H

Fri Jul 01 00:00:00 UTC 2016

Cartilage-specific deletion of Mig-6 results in osteoarthritis-like disorder with excessive articular chondrocyte proliferation.

Proceedings of the National Academy of Sciences of the United States of America

Staal B,Williams BO,Beier F,Vande Woude GF,Zhang YW

Tue Feb 18 00:00:00 UTC 2014

Cartilage-specific deletion of Mig-6 results in osteoarthritis-like disorder with excessive articular chondrocyte proliferation.

Proceedings of the National Academy of Sciences of the United States of America

Staal B,Williams BO,Beier F,Vande Woude GF,Zhang YW

Tue Feb 18 00:00:00 UTC 2014

Downregulation of Mig-6 in nonsmall-cell lung cancer is associated with EGFR signaling.

Molecular carcinogenesis

Li Z,Dong Q,Wang Y,Qu L,Qiu X,Wang E

Sun Jul 01 00:00:00 UTC 2012

Downregulation of Mig-6 in nonsmall-cell lung cancer is associated with EGFR signaling.

Molecular carcinogenesis

Li Z,Dong Q,Wang Y,Qu L,Qiu X,Wang E

Sun Jul 01 00:00:00 UTC 2012

Downregulation of Mig-6 in nonsmall-cell lung cancer is associated with EGFR signaling.

Molecular carcinogenesis

Li Z,Dong Q,Wang Y,Qu L,Qiu X,Wang E

Sun Jul 01 00:00:00 UTC 2012

Bioinformatics

Protein Aliases: ERBB receptor feedback inhibitor 1; Gene 33 polypeptide; MIG-6; Mitogen-inducible gene 6 protein; Mitogen-inducible gene 6 protein homolog; RALT; Receptor-associated late transducer

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Gene Aliases: 1300002F13Rik; RALT; 33; AI788755; ERRFI1; gene 33; GENE-33; MIG-6; MIG6; Ralt; RGD1307599; Xxx

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UniProt ID: (Human) Q9UJM3, (Mouse) Q99JZ7, (Rat) P05432

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Entrez Gene ID: (Human) 54206, (Mouse) 74155, (Rat) 313729

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Function(s)

GTPase activator activity protein binding SH3 domain binding protein kinase binding small GTPase binding kinase binding

Process(es)

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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MIG6/ERRFI1 Polyclonal Antibody

MIG6/ERRFI1 Antibody (11630-1-AP) in ICC/IF

Product Details

11630-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Miscellaneous PubMed (Misc)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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