PA1-32563 detects Melatonin Receptor Type 1B (MT2) from human samples.
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin.
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Protein Aliases: Mel-1B-R; mel1b receptor; melatonin receptor 1B variant b; melatonin receptor MEL1B; Melatonin receptor type 1B
Gene Aliases: FGQTL2; MEL-1B-R; MT2; MTNR1B
UniProt ID: (Human) P49286
Entrez Gene ID: (Human) 4544
Molecular Function: G-protein coupled receptor