OriGene

MYD88 Monoclonal Antibody (OTI1B8), TrueMAB™

Product Image Gallery

MYD88 Antibody in Immunofluorescence (IF) — Anti-MYD88 mouse monoclonal antibody (TA502118) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MYD88(RC202253). (1:100)

MYD88 Antibody in Western Blot (WB) — HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MYD88(RC202253, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-MYD88. (1:500)

MYD88 Antibody in Flow Cytometry (Flow) — HEK293T cells transfected with either RC202253 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-MYD88 antibody (TA502118), and then analyzed by flow cytometry. (1:100)

Product Details

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

1:100

Immunocytochemistry (ICC)

1:100

Immunofluorescence (IF)

1:100

Immunohistochemistry (Paraffin) (IHC (P))

1:150

Western Blot (WB)

1:1000-1:2000

Product Specifications

Species Reactivity

Human, Rat

Host / Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI1B8

Immunogen

Full length human recombinant protein of human MYD88 produced in HEK293T cell.

Conjugate

Unconjugated

Form

liquid

Concentration

0.4 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Target Information

Myeloid differentiation Marker 88 (MyD88) is an adaptor molecule for the Toll/IL-1R and is involved in the inflammatory response induced by IL-1, IL-18 and LPS. MyD88 recruits IRAK to IL-1 receptor complex in response to IL-1. This pathway further leads to activation of NF-kB. MyD88 has a wide tissue distribution.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: mutant myeloid differentiation primary response 88; myeloid differentiation primary response gene (88); myeloid differentiation primary response gene 88; Myeloid differentiation primary response protein MyD88

Gene Aliases: MYD88; MYD88D

UniProt ID: (Human) Q99836, (Rat) Q6Y1S1

Entrez Gene ID: (Human) 4615, (Rat) 301059

Function(s)