Monoamine oxidase A and B catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine. MAOB preferentially degrades benzylamine and phenylethylamine.
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Protein Aliases: adrenalin oxidase; Amine oxidase [flavin-containing] A; Amine oxidase [flavin-containing] B; MAO, brain; MAO, platelet; MAO-A; MAO-B; Monoamine oxidase type A; Monoamine oxidase type B; monoamine oxidase-B; tyramine oxidase
Gene Aliases: 1110061B18Rik; 6330414K01Rik; AA407771; Mao; MAO-A; MAO-B; MAOA; MAOB
Molecular Function: oxidase