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|Tested species reactivity||Mouse|
|Host / Isotype||Rabbit|
|Immunogen||A synthetic peptide from the internal region of mouse Mucolipin 3 conjugated to an immunogenic carrier protein|
|Storage buffer||whole serum|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:300-1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Reconstitute with 100 ul of distilled water.
Centrifuge to remove any insoluble material.
Expressed in the cochlea; particularly in the inner and outer hair cells. Defects in Mcoln3 are the cause of the varitin-waddler (Va) phenotype. Classical Va mice exhibit early-onset hearing loss, vestibular defects, pigmentation abnormalities and perinatal lethality. The phenotype varitin-waddler Jackcon (Va-J), which arose in a cross segregating for Va, is similar but less severe. Belongs to the transient receptor family, polycystin subfamily.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
6720490O21Rik; Mcoln3 mucolipin 3; MGC124245; MGC124246; mucolipin-3; TRPML3; Va; varitint-waddler
6720490O21Rik; Mcoln3; TRPML3; Va