|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Rabbit muscle myosin|
|Contains||<0.1% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunocytochemistry (ICC)||See 1 publications below|
MA5-11748 targets Myosin Skeletal Muscle in IHC (P) applications and shows reactivity with Human samples.
The MA5-11748 immunogen is rabbit muscle myosin.
Myosin is a 480kDa protein known to interact with actin in muscle and in non-muscle cells. It contains two identical heavy chains (200kDa each) and four light chains (15-26kDa). Myosin molecules consist of two major regions: tails (rod) and heads; they aggregate into filaments through the tail region and interact with actin and with ATP through the head region. Multiple forms of myosin heavy chains exist for each muscle type-skeletal, cardiac, smooth and non-muscle isomyosin forms exist in different types of skeletal muscle, depending on the physiological function of the muscle. These are designated at type I (slow-twitch) and type II (fast-twitch).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Ex vivo differentiation of human adult bone marrow stem cells into cardiomyocyte-like cells.
MA5-11748 was used in immunocytochemistry to study the ex vivo differentiation of human adult bone marrow stem cells into cardiomyocyte-like cells
|Shim WS,Jiang S,Wong P,Tan J,Chua YL,Tan YS,Sin YK,Lim CH,Chua T,Teh M,Liu TC,Sim E||Biochemical and biophysical research communications (324:481)||2004|