FIGURE: 1 / 9
Immunogen sequence: MNPAAEAEF NILLATDSYK VTHYKQYPPN TSKVYSYFEC REKKTENSKL RKVKYEETVF YGLQYILNKY LKGKVVTKEK IQEAKDVYKE HFQDDVFNEK GWNYILEKYD GHLPIEIKAV PEGFVIPRGN VLFTVENTDP ECYWLTNWIE TILVQSWYPI TVATNSREQK KILAKYLLET SGNLDGLEYK LHDFGYRGVS SQETAGIGAS AHLVNFKGTD TVAGLALIKK YYGTKDPVPG YSVPAAEHST ITAWGKDHEK DAFEHIVTQF SSVPVSVVSD SYDIYNACEK IWGEDLRHLI VSRSTQAPLI IRPDSGNPLD TVLKVLEILG KKFPVTENSK GYKLLPPYLR V (1-350 aa encoded by BC020691)
Visfatin, also known as pre-B cell colony-enhancing factor, is an adipocytokine that is abundantly secreted by visceral adipose tissue, with insulin mimetic effects. Visfatin mimics insulin signaling by binding to the insulin receptor and reducing glucose release from liver cells, while stimulating glucose utilization in adipocytes and myocytes. Visfatin is also invoved in enhancement of cell proliferation, biosynthesis of nicotinamide mono-and dinucleotide and glucose homeostasis.
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Protein Aliases: DKFZp666B131; EC 22.214.171.124; MGC117256; NAmPRTase; Nicotinamide phosphoribosyltransferase; PBEF; Pre-B cell-enhancing factor; pre-B-cell colony enhancing factor 1; Pre-B-cell colony-enhancing factor 1; Pre-B-cell colony-enhancing factor 1 homolog; Visfatin
Gene Aliases: 1110035O14Rik; AI314458; AI480535; NAmPRTase; NAMPT; PBEF; PBEF1; VF; VISFATIN
Molecular Function: transferase