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NRXN1 Antibody (PA5-49444) in WB
Western blot analysis of NRXN1 in (Lane 1) SH-SY5Y whole cell lysates (20 µg), (Lane 2) human cerebellum lysates (20 µg), (Lane 3) mouse brain lysates (20 µg). Samples probed with NRXN1 Antibody (N-term) (Product # PA5-49444) at a 1:2000 dilution, followed by Secondary Goat Rabbit IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size : 47 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
Product Details
PA5-49444
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 77-110 amino acids from the N-terminal region of human NRXN1.
Conjugate
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2634898
Target Information
Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. May play a role in formation or maintenance of synaptic junctions. May mediate intracellular signaling. May play a role in angiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha-latrotoxin receptor (calcium-dependent); DKFZp313P2036; FLJ35941; Neurexin 1alpha; neurexin I; Neurexin I-alpha; Neurexin I-beta; Neurexin-1; Neurexin-1-alpha; Neurexin-1-beta
Gene Aliases: 1700062G21Rik; 9330127H16Rik; A230068P09Rik; Hs.22998; KIAA0578; mKIAA0578; NRXN1; PTHSL2; SCZD17
UniProt ID: (Human) Q9ULB1, (Mouse) Q9CS84
Entrez Gene ID: (Human) 9378, (Mouse) 18189
vesicle docking involved in exocytosis
cell adhesion
signal transduction
chemical synaptic transmission
neurotransmitter secretion
synapse assembly
learning
adult behavior
social behavior
vocal learning
neuromuscular process controlling balance
protein heterotetramerization
positive regulation of synapse assembly
positive regulation of synaptic transmission, glutamatergic
prepulse inhibition
regulation of insulin secretion involved in cellular response to glucose stimulus
vocalization behavior
positive regulation of synapse maturation
postsynaptic membrane assembly
gephyrin clustering involved in postsynaptic density assembly
neuroligin clustering involved in postsynaptic membrane assembly
postsynaptic density protein 95 clustering
positive regulation of excitatory postsynaptic potential
regulation of grooming behavior
neuron cell-cell adhesion
axon guidance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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