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The homeodomain-containing transcription factor NKX3-1 is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3-1 protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Drosophila NK-3 transcription factor, locus 1; Homeobox protein NK-3 homolog A; Homeobox protein Nkx-3.1; NKX3-1 antibody; prostate-specific ag
Gene Aliases: bagpipe; Bax; Nkx-3.1; Nkx3-1; NKX3.1; NKX3A
UniProt ID: (Mouse) P97436
Entrez Gene ID: (Mouse) 18095
Molecular Function: homeodomain transcription factor