|Immunocytochemistry (ICC)||10 µg/ml|
|Immunofluorescence (IF)||10 ug/ml|
|Immunoprecipitation (IP)||Assay dependent|
|Western Blot (WB)||1:100-1:1000|
|Western Blot (WB)||See 2 publications below|
|Blocking Assay (BLOCK)||See 1 publications below|
|Tested Species reactivity||Human, Mouse|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||A431 trypsinized membranes.|
|Storage buffer||PBS with 1mg/ml BSA|
|Contains||0.05% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
MA1-2003 detects P-cadherin from human and mouse samples.
MA1-2003 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~120 kDa protein representing P-cadherin from A431 cell extract. MA1-2003 can also be used in immunoprecipitation and immunofluorescence procedures.
The MA1-2003 immunogen is A431 trypsinized membranes.
The cadherin superfamily of proteins are a group of calcium mediated cell-cell adhesion molecules. Cadherins are responsible for a whole range of processes including development, wound healing, cell-cell signaling, cell growth and differentiation. N-cadherin is found in many locations including cardiac adherins junctions, oral squamous epithelial cells, and breast epithelial cells. Studies have linked N-cadherin to cancer metastasis by showing the aggressive tumor cells had preferentially turned on N-cadherin as opposed to E- or P-cadherin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cadherin 3, type 1, P-cadherin (placental); Cadherin-3; calcium-dependent adhesion protein, placental; P-cadherin; Placental cadherin; Placental-cadherin; RPE-specific cadherin
Gene Aliases: AI385538; Cadp; CDH3; CDHP; HJMD; P-cadherin; PCAD
Molecular Function: cadherin
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