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PA1-24547 detects G Protein-Coupled Receptor GPR85/SREB2 in Human samples.
GPR85, a member of the SREB (Super-Conserved Receptor Expressed in Brain) family of GPCRs, is an Orphan-A GPCR with an unknown ligand. The rat counterpart of SREB2 is involved in the development of the cerebral cortex. GPR85 has been reported to be expressed in several areas of human and rat CNS (Matsumoto et al., 2000), as well as in genital organs. ESTs have been isolated from B-cell/lung/testis, brain, testis, and embryo libraries, as well as many mouse tissue libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ50993; FLJ51159; FLJ99433; Probable G-protein coupled receptor 85; Rgpr85; seven transmembrane helix receptor; Super conserved receptor expressed in brain 2
Gene Aliases: GPR85; SREB; SREB2
UniProt ID: (Human) P60893
Entrez Gene ID: (Human) 54329
Molecular Function: G-protein coupled receptor transmembrane signal receptor
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