Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
PA1-75463 specifically detects Tobramycin.
PA1-75463 has been successfully used in ELISA applications.
The PA1-75463 immunogen is Tobramycin-BSA.
Tobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius with bacteriostatic activity. Following active transport into the cell, tobramycin binds irreversibly to a specific aminoglycoside receptor on the bacterial 30S ribosomal subunit and interferes with the initiation complex between messenger RNA and the 30S subunit, thereby inhibiting initiation of protein synthesis, consequently leading to bacterial cell death. In addition, tobramycin induces misreading of the mRNA template causing incorrect amino acids to be incorporated into the growing polypeptide chain, consequently interfering with protein elongation. [National Center for Biotechnology Information. PubChem Compound Database; CID=36294].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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