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Immunogen sequence: ARSRKVEEDE YEDSSSNQKW VLAPKSQDTD VTLILNKLLR EYD
GABRG3 is a family of proteins involved in the GABAergic neurotransmission of the mammalian central nervous system. GABRG3 is a member of the GABA-A receptor gene family of heteromeric pentameric ligand-gated ion channels through which GABA, the major inhibitory neurotransmitter in the mammalian brain, acts. GABA-A receptors are the site of action of a number of important pharmacologic agents including barbiturates, benzodiazepines, and ethanol (summary by Whiting et al., 1999). For additional general information about the GABA-A receptor gene family, see GABRA1 (MIM 137160).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CAE2; ECA2; GABA(A) receptor subunit gamma-3; GABA(G) receptor; GABA(G) receptor, gamma 3; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, gamma 3; Gamma-aminobutyric acid receptor subunit gamma-3; GEFSP3
Gene Aliases: GABRG3
UniProt ID: (Human) Q99928
Entrez Gene ID: (Human) 2567
Molecular Function: ligand-gated ion channel
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