Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Peptide sequence: SMGPRSGEHQ RASRIPSQFS KEERVAMKEA LKGAIQIPTV TFSSEKSNTT
Sequence homology: Guinea Pig: 91%; Human: 100%
Bidirectional N-fatty-acyl amino acid synthase/hydrolase that regulates the production of N-fatty-acyl amino acids. These metabolites are endogenous chemical uncouplers of mitochondrial respiration. In an UCP1-independent manner, maybe through interaction with mitochondrial transporters, they promote proton leakage into the mitochondrial matrix. Thereby, this secreted protein may indirectly regulate the bodily dissipation of chemical energy as heat through thermogenic respiration. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: N-fatty-acyl-amino acid synthase/hydrolase PM20D1; Peptidase M20 domain-containing protein 1
Gene Aliases: Cps1; PM20D1
UniProt ID: (Human) Q6GTS8
Entrez Gene ID: (Human) 148811
Molecular Function: hydrolase
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