Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
The antibody detects endogenous levels of total TP53I11 protein.
TP53I11 is a 177 amino acid tumor suppressor belonging to the p53-induced protein gene (PIG) family. The PIG gene family encodes redox-controlling proteins that are involved in p53 tumor suppressor activity. It is suggested that PIG11 is involved in arsenic trioxide As(2)O(3)-induced apoptosis in certain cell lines and may play a significant role in tumor suppression through promotion of cell apoptosis. The gene encoding PIG11 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: p53-induced gene 11 protein; transformation related protein 53 inducible protein 11; Tumor protein p53-inducible protein 11
Gene Aliases: PIG11; TP53I11; Trp53i11
UniProt ID: (Human) O14683, (Rat) B3DMA0
Entrez Gene ID: (Human) 9537, (Rat) 311209
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