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Immunogen sequence: TNGVAISDPS RCPQPAASSA SEQRRPRFQA GTWSRQCRIE EEEEVEQELL SHSWGRETKN GPTDHSNSTT WHRLHPTDGS SGQNSKVGTG MSKSASFAFE FPKD
Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 75%.
PRAGMIN is also known as SGK223 (sugen kinase 223). The rat homolog was originally identified in a yeast two-hybrid screen for Rnd2 effector proteins expressed in neural cells. Rat Pragmin was found to stimulate RhoA activity for the regulation of neurite outgrowth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Inactive tyrosine-protein kinase PRAG1; PEAK1-related kinase-activating pseudokinase 1; Pragmin; SgK223; Sugen kinase 223
Gene Aliases: PRAG1; PRAGMIN; SGK223
UniProt ID: (Human) Q86YV5
Entrez Gene ID: (Human) 157285
Molecular Function: non-receptor serine/threonine protein kinase protein modifying enzyme
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