Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: EVNEDISQEL MDSDSGNYLK RALQLSDRKN LVPRDEELCI YENKVTPLHF LVAQGSVEQV RLLLAHEVDV DCQTASGYTP LLIAAQDQQP DLCALLLAHG ADANRVDEDG WAPLHFAAQN GDDGTARLLL DHGACVDAQE R
Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 77%.
ANKK1 serine/threonine kinase is a member of the RIPK family and is closely linked to the DRD2 gene. ANKK1 is closely linked to DRD2 gene on chr 11, and a well studied restriction fragment length polymorphism designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene, where it causes a nonconservative amino acid substitution. It is not clear if ANKK1 plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ankyrin repeat and protein kinase domain-containing protein 1; Protein kinase PKK2; SgK288; Sugen kinase 288; X-kinase
Gene Aliases: ANKK1; PKK2; SGK288
UniProt ID: (Human) Q8NFD2
Entrez Gene ID: (Human) 255239
Molecular Function: non-receptor serine/threonine protein kinase
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