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Immunogen sequence: MNPVYSPVQP GAPYGNPKNM AYTGYPTAYP AAAPAYNPSL YPTNSPSYAP EFQFLHSAYA TLLMKQAWPQ NSSSCGTEGT FHLPVDTGTE NRTY
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 99%.
In cancer context, protects cells from induced-DNA damage and apoptosis. Acts, at least in part, through PI3K/AKT/NFKB signaling pathway and by preventing POLB degradation. Decreases POLB ubiquitation and stabilizes its protein levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: family with sequence similarity 168, member A; Protein FAM168A; Tongue cancer chemotherapy resistance-associated protein 1
Gene Aliases: FAM168A; KIAA0280; TCRP1
UniProt ID: (Human) Q92567
Entrez Gene ID: (Human) 23201
Molecular Function: myelin protein
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