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Immunogen sequence: ESPESSAIES TQSTPQKGRG RPSKTPSPSQ PKKNVRVGRS KQAATKENDS SEEVDVFQGS SPVDDIPQEE TEEEEVSTVN VRRRSAKRER
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 81%.
This gene encodes a protein that interacts with the conserved protein complex termed cohesin. The cohesin complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor-suppressor gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: androgen induced inhibitor of proliferation; Androgen-induced proliferation inhibitor; Androgen-induced prostate proliferative shutoff-associated protein AS3; androgen-induced shutoff 3; Sister chromatid cohesion protein PDS5 homolog B
Gene Aliases: APRIN; AS3; CG008; KIAA0979; PDS5B
UniProt ID: (Human) Q9NTI5
Entrez Gene ID: (Human) 23047
Molecular Function: chromatin/chromatin-binding, or -regulatory protein
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