Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: YRNDYTQGCEP GHRQRDHESR YQNHSSKSSG RSGRSSYKSK HRIHHSTSHR RSHGKSHRR
Highest antigen sequence identity to the following orthologs - mouse 73%, rat 78%.
CLK1 is a dual specificity kinase that phosphorylates PTP-1B and members of the SR family of splicing factors. It is thought to be involved in neuronal differentiation and mRNA splicing. Therefore, the encoded protein may play an indirect role in governing splice site selection.
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Protein Aliases: CDC-like kinase 1; CDC28/CDC2-like kinase; Dual specificity protein kinase CLK1; Protein kinase CLK1; protein tyrosine kinase STY
Gene Aliases: CLK; CLK/STY; CLK1; STY
UniProt ID: (Human) P49759
Entrez Gene ID: (Human) 1195
Molecular Function: non-receptor serine/threonine protein kinase
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