Glucose is fundamental to the metabolism of mammalian cells. Several glucose transporter protein (Glut) isoforms have been identified and shown to function in response to insulin and IGF-1 induced signaling. GLUT-3 is detectable in a few normal cell type spermatids in testis with active spermatogenesis, placental trophoblast membranes, and neurons in brain. GLUT-3 staining is also detectable in human cancers including those of the ovary, lung, and testis.
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Protein Aliases: brain; facilitated glucose transporter member 3; glucose transporter type 3; Glucose transporter type 3, brain; GLUT-3; GLUT3; solute carrier family 2; solute carrier family 2 (facilitated glucose transporter), member 3; Solute carrier family 2, facilitated glucose transporter member 3
Gene Aliases: GLUT3; SLC2A3
UniProt ID: (Human) P11169
Entrez Gene ID: (Human) 6515