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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: complement factor H-related 3; Complement factor H-related protein 3; DOWN16; FHR-3; H factor-like 4; H factor-like protein 3
Gene Aliases: CFHL3; CFHR3; DOWN16; EG624286; FHR-3; FHR3; HLF4
UniProt ID: (Human) Q02985
Entrez Gene ID: (Human) 10878, (Mouse) 624286
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