Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Immunogen sequence: PAPCSCAGTL VDCGRRGLTW ASLPTAFPVD TTELVLTGNN LTALPPGLLD ALPALRTAHL GANPWRCDCR LVPLRAWLAG RPERAPYRDL RCVAPPALRG RLLPYLAEDE LRAACAPGPL C; Positive Samples: LO2, THP-1, Mouse heart, Mouse brain, Rat brain; Cellular Location: Membrane, Single-pass type I membrane protein
CD42a is a single-chain membrane glycoprotein that forms a noncovalent complex with CD42b. CD42b, also known as glycoprotein Ib a (GPIb a) is a membrane glycoprotein that is composed of a and b chains. The CD42b b chain is also designated CD42c, and is expressed on platelets and megakaryoctes. CD42a and CD42b are also present on platelets and mega-karyocytes, and the complex is a major component of the platelet surface. The complex acts as a receptor for von Willebrand's factor and as a von Willebrand's factor-dependent adhesion receptor.
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Protein Aliases: Antigen CD42b-beta; CD42c; glycoprotein Ib (platelet), beta polypeptide; glycoprotein Ib, beta polypeptide; GP-Ib beta; GPIb-beta; GPIbB; nuclear localization signal deleted in velocardiofacial syndrome; Platelet glycoprotein Ib beta chain; platelet membrane glycoprotein Ib beta; truncated platelet membrane glycoprotein Ib beta
Gene Aliases: BDPLT1; BS; CD42C; GP1BB; GPIBB; GPIbbeta
UniProt ID: (Human) P13224, (Mouse) P56400, (Rat) Q9JJM7
Entrez Gene ID: (Human) 2812, (Mouse) 14724, (Rat) 116727
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