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Search Thermo Fisher Scientific
Immunogen sequence: IFEPHVAVRD AAKMNIPTVG IVDTNCNPCL ITYPVPGNDD SPLAVHLYCR LFQTAITRAK EKRQQVEALY RLQGQKEPGD QGPAHPPGAD
Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 70%.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S2 family. Alternatively spliced transcript variants have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 28S ribosomal protein S2, mitochondrial; MRP-S2; Small ribosomal subunit protein uS2m
Gene Aliases: CGI-91; MRP-S2; MRPS2; S2mt
UniProt ID: (Human) Q9Y399
Entrez Gene ID: (Human) 51116
Molecular Function: ribosomal protein
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