Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: QVDLPMGGVK ALTIDHLAVN DVMLESLRGE GQGLVCDLCN DREVEKRCQT CKANLCHFCC QAHRRQKKTT YHTMVDLKDL KGYSRIGKPI LCPVHPAEEL RLFCEFCDRP VCQDCVVGEH REHPCDFTSN VIHKHGDSVW ELLKGTQPHV EALEEALAQI HIINSALQKR VEAVAADVRT FSEGYIKAIE EHRDKLLKQL EDIRAQKENS LQLQKAQLEQ LLADMRTGVE FTEHLLTSGS DLEILITKRV VVERLRKLNK VQYSTRPGVN DKIRFCPQEK AGQCRGYEIY DLHRAREKQT A; Positive Samples: BxPC-3, 293T, HeLa, Mouse brain, Mouse pancreas; Cellular Location: Cytoplasm, Nucleus
TRIM45 is a member of the tripartite motif family. It may function as a transcriptional repressor of the mitogen-activated protein kinase pathway. Alternatively spliced transcript variants have been described. TRIM45 belongs to a family of tripartite motif (TRIM) proteins that play important roles in a variety of cellular functions, including cell proliferation, differentiation, development, oncogenesis, and apoptosis.
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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: E3 ubiquitin-protein ligase TRIM45; FLJ13181; RING finger protein 99; Tripartite motif-containing protein 45
Gene Aliases: 4921530N01Rik; Trim45
UniProt ID: (Mouse) Q6PFY8
Entrez Gene ID: (Mouse) 229644
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