Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Immunogen sequence: MLRLQMTDGH ISCTAVEFSY MSKISLNTPP GTKVKLSGIV DIKNGFLLLN DSNTTVLGGE VEHLIEKWEL QRSLSKHNRS NIGTEGGPPP FVPFGQKCVS HVQVDSRELD RRKTLQVTMP VKPTNDNDEF EKQRTAAIAE VAKSKETKTF GGGGGGARSN LNMNAAGNRN REVLQKEKST KSEGKHEGVY RELVDEKALK HITEMGFSKE ASRQALMDNG; Positive Samples: U2OS; Cellular Location: Cytoplasm, Nucleus
TDRD3 belongs to the tudor domain group of proteins, which are prevalent among proteins involved in RNA metabolism. TDRD3 is widely expressed and localizes predominantly in the cytoplasm. It is detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas. Overexpression of TDRD3 in cells induces the formation of stress granules. Multiple isoforms of TDRD3 exist due to alternative splicing variants. In humans, the gene is located on chromosome 13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Tudor domain-containing protein 3
Gene Aliases: TDRD3
UniProt ID: (Human) Q9H7E2
Entrez Gene ID: (Human) 81550
Molecular Function: RNA splicing factor
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