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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 12 and 267 of Human PABP5|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-31596 targets PABP5 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-31596 immunogen is recombinant fragment corresponding to a region within amino acids 12 and 267 of Human PABP5.
This gene encodes a protein that binds to the polyA tail found at the 3 and apos; end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. This gene is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
PABP-5; PABP5; poly(A) binding protein, cytoplasmic 5; Polyadenylate-binding protein 5