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Product Details
PA1-41564
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat,
Xenopus
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues 400-450 of human PACSIN 2.
Conjugate
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 0.2% gelatin
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_2161866
Product Specific Information
This antibody is predicted to react with mouse, rat, canine, bovine, and chicken based on sequence homology.
Target Information
PACSIN 2, a 486 AA phosphoprotein is a novel member of the PACSIN family of cytoplasmic adapter proteins. It is an isoform of PACSIN with a CDC15 N-terminal domain, a C-terminal SH3 domain, 3 conserved regions specific to the PACSIN family, and 3 asn-pro-phe (NPF) motifs, which potentially bind to EH domains. This protein is known to display a ubiquitous expression pattern with the highest levels of expression in brain. Reports suggest that PACSIN 2 participates in the organization of the actin cytoskeleton, the regulation of vesicular traffic. It also participates in endocytic internalization and endocytic receptor recycling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cytoplasmic phosphoprotein PACSIN2; Protein kinase C and casein kinase substrate in neurons 2 protein; Protein kinase C and casein kinase substrate in neurons protein 2; RP3-437M21.1; SdpII; SdpIIsyndapin II; Synaptic dynamin-associated protein II; syndapin 2; Syndapin II; Syndapin-2; Syndapin-II; syndapin2; x-PACSIN2
Gene Aliases: AI197433; PACSIN2; SDPII; XELAEV_18019736mg
UniProt ID: (Human) Q9UNF0, (Rat) Q9QY17, (Mouse) Q9WVE8, (Xenopus) Q9DDA9
Entrez Gene ID: (Human) 11252, (Rat) 124461, (Mouse) 23970, (Xenopus) 398138
Molecular Function:
actin or actin-binding cytoskeletal protein
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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