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Invitrogen
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
- | View 3 publications 3 publications |
Immunohistochemistry (IHC) |
Assay-dependent | View 3 publications 3 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
- | View 1 publication 1 publication |
Immunocytochemistry (ICC/IF) |
- | View 3 publications 3 publications |
ELISA (ELISA) |
Assay-dependent | - |
Miscellaneous PubMed (Misc) |
- | View 1 publication 1 publication |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Published species |
Human, Mouse |
Host/Isotype |
Mouse / IgG2a |
Class |
Monoclonal |
Type |
Antibody |
Clone |
SAM11 |
Immunogen |
A synthetic peptide corresponding to the N-terminal of the human PAR2 receptor. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.5 mg/mL |
Purification |
Protein A |
Storage buffer |
PBS, pH 7.4 |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
RRID |
AB_2533199 |
Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: coagulation factor II (thrombin) receptor-like 1; Coagulation factor II receptor-like 1; G-protein coupled receptor 11; PAR-2; protease-activated receptor 2; Proteinase-activated receptor 2; Proteinase-activated receptor 2, alternate cleaved 1; Proteinase-activated receptor 2, alternate cleaved 2; Thrombin receptor-like 1
Gene Aliases: F2RL1; GPR11; PAR2
UniProt ID: (Human) P55085
Entrez Gene ID: (Human) 2150
Molecular Function:
G-protein coupled receptor
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