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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||Purified recombinant fragment of PARL (aa112-167) expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1/500 - 1/2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-15428 targets PARL in WB applications and shows reactivity with Human samples.
The MA5-15428 immunogen is purified recombinant fragment of PARL (aa112-167) expressed in E. Coli.
This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Mitochondrial intramembrane cleaving protease PARL; mitochondrial intramembrane-cleaving protease PARL; PARL; Presenilins-associated rhomboid-like protein, mitochondrial; PRO2207; PSARL; PSARL1; PSENIP2; RHBDS1; rhomboid 7 homolog 1
PARL; PRO2207; PSARL; PSARL1; PSENIP2; RHBDS1