MA5-15657 targets PAX6 in FACS and WB applications and shows reactivity with Human samples.
The MA5-15657 immunogen is purified recombinant fragment of human PAX6 expressed in E. Coli.
MA5-15657 detects PAX6 which has a predicted molecular weight of approximately 46kDa.
This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding either the same or different isoform have been found for this gene.
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Protein Aliases: AN; AN2; Aniridia type II protein; D11S812E; Dickie's small eye; MGC17209; MGDA; Oculorhombin; paired box gene 6; paired box homeotic gene-6; Paired box protein Pax-6; PAX6; small eye; WAGR
Gene Aliases: 1500038E17Rik; AEY11; AN; AN2; D11S812E; Dey; FVH1; Gsfaey11; MGDA; Pax-6; PAX6; Sey; WAGR