Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: PDZ and LIM domain 2 (mystique); PDZ and LIM domain protein 2; PDZ-LIM protein mystique
Gene Aliases: MYSTIQUE; PDLIM2; PP6345; SLIM
UniProt ID: (Human) Q96JY6
Entrez Gene ID: (Human) 64236
Molecular Function: actin or actin-binding cytoskeletal protein