Positive Control: PC-3M, LOVO, SH-SY-5Y, rat brain tissue, human liver cancer tissue, human thyroid gland tissue, mouse skeletal muscle tissue, human kidney tissue.
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family.
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Protein Aliases: 6-phosphofructo-1-kinase; 6-phosphofructokinase type A; 6-phosphofructokinase, muscle type; ATP-dependent 6-phosphofructokinase, muscle type; ATP-PFK; PFK-A; Phosphofructo-1-kinase isozyme A; phosphofructokinase 1; phosphofructokinase muscle; phosphofructokinase, polypeptide X; phosphofructokinase-M; Phosphohexokinase; protein phosphatase 1, regulatory subunit 122
Gene Aliases: ATP-PFK; GSD7; PFK-1; PFK1; PFKA; PFKM; PFKX; PPP1R122
UniProt ID: (Human) P08237
Entrez Gene ID: (Human) 5213