The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene.
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Protein Aliases: Noradrenaline N-methyltransferase; PENT; phenylethanolamine N-methylase; Phenylethanolamine N-methyltransferase; PNMT; PNMT_HUMAN; PNMTase
Gene Aliases: PENT; PNMT; PNMTase