Product References
Liraglutide Attenuates Hepatic Oxidative Stress, Inflammation, and Apoptosis in Streptozotocin-Induced Diabetic Mice by Modulating the Wnt/β-Catenin Signaling Pathway.
Mediators of inflammation
Yu J,Zhao Y,Xu L,Li W,Zhang H,Ping F,Li Y
Fri Feb 10 00:00:00 UTC 2023
Casein Kinase 1α Regulates Testosterone Synthesis and Testis Development in Adult Mice.
Endocrinology
Guo H,Zhang D,Zhou Y,Sun L,Li C,Luo X,Liu J,Cui S
Mon Mar 13 00:00:00 UTC 2023
Loss of CBX2 causes genomic instability and Wnt activation in high grade serous ovarian carcinoma cells.
Molecular carcinogenesis
Ma Y,Liu L,Wei Z,Zhu M,Huang L,Wang S,Yi X,Ying F,Zhao S,Cai J,Wang Z,Sun S
Sat Apr 01 00:00:00 UTC 2023
The effect and a mechanistic evaluation of polystyrene nanoplastics on a mouse model of type 2 diabetes.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Wang Y,Wei Z,Xu K,Wang X,Gao X,Han Q,Wang S,Chen M
Wed Mar 01 00:00:00 UTC 2023
GIPC2 is a tumor suppressor gene for acute myeloid leukemia and induces apoptosis of leukemia cells by regulating the PI3K/AKT pathway.
Epigenomics
Zhao J,Liu J,Liu S,Tian S,Yuan H,Li S
Wed Mar 01 00:00:00 UTC 2023
Young and undamaged recombinant albumin alleviates T2DM by improving hepatic glycolysis through EGFR and protecting islet β cells in mice.
Journal of translational medicine
Liu H,Ju A,Dong X,Luo Z,Tang J,Ma B,Fu Y,Luo Y
Mon Feb 06 00:00:00 UTC 2023
Chemical Constituents and Hypoglycemic Mechanisms of Dendrobium nobile in Treatment of Type 2 Diabetic Rats by UPLC-ESI-Q-Orbitrap, Network Pharmacology and In Vivo Experimental Verification.
Molecules (Basel, Switzerland)
Li Z,Zeng M,Geng K,Lai D,Xu Z,Zhou W
Thu Mar 16 00:00:00 UTC 2023
Design, synthesis and bioevaluation of 1,2,4-thiadiazolidine-3,5-dione derivatives as potential GSK-3β inhibitors for the treatment of Alzheimer's disease.
Bioorganic chemistry
Dong Y,Lu J,Zhang S,Chen L,Wen J,Wang F,Mao Y,Li L,Zhang J,Liao S,Dong L
Mon May 01 00:00:00 UTC 2023
Ursolic Acid Suppresses Colorectal Cancer by Down-Regulation of Wnt/β-Catenin Signaling Pathway Activity.
Journal of agricultural and food chemistry
Zhao H,Tang S,Tao Q,Ming T,Lei J,Liang Y,Peng Y,Wang M,Liu M,Yang H,Ren S,Xu H
Wed Mar 08 00:00:00 UTC 2023
Chebulagic acid suppresses gastric cancer by inhibiting the AURKA/β-catenin/Wnt pathway.
Frontiers in pharmacology
Zhao J,Shi Y,Ma Y,Pan L,Wang Y,Yuan L,Dong J,Ying J
Tue Mar 21 00:00:00 UTC 2023
Hastatoside attenuatescarbon tetrachloride-induced liver fibrosis by targeting glycogen synthase kinase-3β.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Du C,Dong J,Wang Q,Xu C,Feng S,Feng R,Lv X,Li J,Zhang L,Huang C,Ma T
Sun Jan 01 00:00:00 UTC 2023
Hastatoside attenuatescarbon tetrachloride-induced liver fibrosis by targeting glycogen synthase kinase-3β.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Du C,Dong J,Wang Q,Xu C,Feng S,Feng R,Lv X,Li J,Zhang L,Huang C,Ma T
Sun Jan 01 00:00:00 UTC 2023
Hastatoside attenuatescarbon tetrachloride-induced liver fibrosis by targeting glycogen synthase kinase-3β.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Du C,Dong J,Wang Q,Xu C,Feng S,Feng R,Lv X,Li J,Zhang L,Huang C,Ma T
Sun Jan 01 00:00:00 UTC 2023
Hastatoside attenuatescarbon tetrachloride-induced liver fibrosis by targeting glycogen synthase kinase-3β.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Du C,Dong J,Wang Q,Xu C,Feng S,Feng R,Lv X,Li J,Zhang L,Huang C,Ma T
Sun Jan 01 00:00:00 UTC 2023
Receptor tyrosine kinase C-kit promotes a destructive phenotype of FLS in osteoarthritis via intracellular EMT signaling.
Molecular medicine (Cambridge, Mass.)
Cao X,Wu S,Wang X,Huang J,Zhang W,Liang C
Thu Mar 23 00:00:00 UTC 2023
Inhibition of NLRP1-Dependent Pyroptosis Prevents Glycogen Synthase Kinase-3β Overactivation-Induced Hyperphosphorylated Tau in Rats.
Neurotoxicity research
Liu X,Song W,Yu Y,Su J,Shi X,Yang X,Wang H,Liu P,Zou L
Sat Oct 01 00:00:00 UTC 2022
Astragaloside IV Alleviates Intestinal Barrier Dysfunction via the AKT-GSK3β-β-Catenin Pathway in Peritoneal Dialysis.
Frontiers in pharmacology
He J,Wang M,Yang L,Xin H,Bian F,Jiang G,Zhang X
Sat Jul 16 00:00:00 UTC 2022
Insulin and liraglutide attenuate brain pathology in diabetic mice by enhancing the Wnt/β-catenin signaling pathway.
Experimental and therapeutic medicine
Zhao Y,Yu J,Ping F,Xu L,Li W,Zhang H,Li Y
Fri Jul 01 00:00:00 UTC 2022
Chinese Herbal Extracts Exert Neuroprotective Effect in Alzheimer's Disease Mouse Through the Dopaminergic Synapse/Apoptosis Signaling Pathway.
Frontiers in pharmacology
Huang Q,Zhang C,Qu S,Dong S,Ma Q,Hao Y,Liu Z,Wang S,Zhao H,Shi Y
Sat Mar 19 00:00:00 UTC 2022
CCDC65, a Gene Knockout that leads to Early Death of Mice, acts as a potentially Novel Tumor Suppressor in Lung Adenocarcinoma.
International journal of biological sciences
Zhang Z,Xu P,Hu Z,Fu Z,Deng T,Deng X,Peng L,Xie Y,Long L,Zheng D,Shen P,Zhang M,Gong B,Zhu Z,Lin J,Chen R,Liu Z,Yang H,Li R,Fang W
Wed Jan 04 00:00:00 UTC 2023
Fatty acid-binding protein 5 aggravates pulmonary artery fibrosis in pulmonary hypertension secondary to left heart disease via activating wnt/β-catenin pathway.
Journal of advanced research
Lei Q,Yu Z,Li H,Cheng J,Wang Y
Thu Sep 01 00:00:00 UTC 2022
Inhibition of FAM83D displays antitumor effects in glioblastoma via down-regulation of the AKT/Wnt/β-catenin pathway.
Environmental toxicology
Wang J,Quan Y,Lv J,Gong S,Ren P
Wed Jun 01 00:00:00 UTC 2022
Fufang Xueshuantong Improves Diabetic Cardiomyopathy by Regulating the Wnt/β-Catenin Pathway.
International journal of endocrinology
Peng M,Liu H,Ji Q,Ma P,Niu Y,Ning S,Sun H,Pang X,Yang Y,Zhang Y,Han J,Hao G
Sat Oct 15 00:00:00 UTC 2022
Psoralen alleviates radiation-induced bone injury by rescuing skeletal stem cell stemness through AKT-mediated upregulation of GSK-3β and NRF2.
Stem cell research & therapy
Yin BF,Li ZL,Yan ZQ,Guo Z,Liang JW,Wang Q,Zhao ZD,Li PL,Hao RC,Han MY,Li XT,Mao N,Ding L,Chen DF,Gao Y,Zhu H
Tue Jun 07 00:00:00 UTC 2022
The transcript ENST00000444125 of lncRNA LINC01503 promotes cancer stem cell properties of glioblastoma cells via reducing FBXW1 mediated GLI2 degradation.
Experimental cell research
Wei P,Jiang J,Xiao M,Zeng M,Liu X,Zhao B,Chen F
Tue Mar 01 00:00:00 UTC 2022
Asafoetida exerts neuroprotective effect on oxidative stress induced apoptosis through PI3K/Akt/GSK3β/Nrf2/HO-1 pathway.
Chinese medicine
Huang Q,Zhang C,Dong S,Han J,Qu S,Xie T,Zhao H,Shi Y
Wed Jul 06 00:00:00 UTC 2022
GLP-1 agonist liraglutide improves ouabain-induced mania and depressive state via GSK-3β pathway.
Journal of receptor and signal transduction research
Çiçekli MN,Tiryaki ES,Altun A,Günaydın C
Sat Oct 01 00:00:00 UTC 2022
Deficiency of M-LP/Mpv17L leads to development of β-cell hyperplasia and improved glucose tolerance via activation of the Wnt and TGF-β pathways.
Biochimica et biophysica acta. Molecular basis of disease
Iida R,Ueki M,Yasuda T
Tue Mar 01 00:00:00 UTC 2022
Deficiency of M-LP/Mpv17L leads to development of β-cell hyperplasia and improved glucose tolerance via activation of the Wnt and TGF-β pathways.
Biochimica et biophysica acta. Molecular basis of disease
Iida R,Ueki M,Yasuda T
Tue Mar 01 00:00:00 UTC 2022
BK Channel Deficiency in Osteoblasts Reduces Bone Formation via the Wnt/β-Catenin Pathway.
Molecules and cells
Jiang L,Yang Q,Gao J,Yang J,He J,Xin H,Zhang X
Tue Aug 31 00:00:00 UTC 2021
Glutaredoxin 1 protects neurons from oxygen-glucose deprivation/reoxygenation (OGD/R)-induced apoptosis and oxidative stress via the modulation of GSK-3β/Nrf2 signaling.
Journal of bioenergetics and biomembranes
Qiu Z,Li X,Duan C,Li R,Han L
Sun Aug 01 00:00:00 UTC 2021
CLIC1 Inhibition Protects Against Cellular Senescence and Endothelial Dysfunction Via the Nrf2/HO-1 Pathway.
Cell biochemistry and biophysics
Lu D,Le Y,Ding J,Dou X,Mao W,Zhu J
Tue Jun 01 00:00:00 UTC 2021
Loss of PHLDA1 has a protective role in OGD/R-injured neurons via regulation of the GSK-3β/Nrf2 pathway.
Human & experimental toxicology
Yang F,Chen R
Mon Nov 01 00:00:00 UTC 2021
Apelin/APJ-Manipulated CaMKK/AMPK/GSK3β Signaling Works as an Endogenous Counterinjury Mechanism in Promoting the Vitality of Random-Pattern Skin Flaps.
Oxidative medicine and cellular longevity
Lou ZL,Zhang CX,Li JF,Chen RH,Wu WJ,Hu XF,Shi HC,Gao WY,Zhao QF
Tue May 18 00:00:00 UTC 2021
Role of Epigallocatechin Gallate in Glucose, Lipid, and Protein Metabolism and L-Theanine in the Metabolism-Regulatory Effects of Epigallocatechin Gallate.
Nutrients
Lin L,Zeng L,Liu A,Yuan D,Peng Y,Zhang S,Li Y,Chen J,Xiao W,Gong Z
Wed Nov 17 00:00:00 UTC 2021
Azathioprine pretreatment ameliorates myocardial ischaemia reperfusion injury in diabetic rats by reducing oxidative stress, apoptosis, and inflammation.
Clinical and experimental pharmacology & physiology
Lu C,Liu L,Chen S,Niu J,Li S,Xie W,Cheng X
Wed Dec 01 00:00:00 UTC 2021
Azathioprine pretreatment ameliorates myocardial ischaemia reperfusion injury in diabetic rats by reducing oxidative stress, apoptosis, and inflammation.
Clinical and experimental pharmacology & physiology
Lu C,Liu L,Chen S,Niu J,Li S,Xie W,Cheng X
Wed Dec 01 00:00:00 UTC 2021
Azathioprine pretreatment ameliorates myocardial ischaemia reperfusion injury in diabetic rats by reducing oxidative stress, apoptosis, and inflammation.
Clinical and experimental pharmacology & physiology
Lu C,Liu L,Chen S,Niu J,Li S,Xie W,Cheng X
Wed Dec 01 00:00:00 UTC 2021
Perilipin 5 ameliorates high-glucose-induced podocyte injury via Akt/GSK-3β/Nrf2-mediated suppression of apoptosis, oxidative stress, and inflammation.
Biochemical and biophysical research communications
Feng J,Xie L,Yu X,Liu C,Dong H,Lu W,Kong R
Fri Mar 12 00:00:00 UTC 2021
Knockdown of ST6Gal-I expression in human hepatocellular carcinoma cells inhibits their exosome-mediated proliferation- and migration-promoting effects.
IUBMB life
Wang L,Chen X,Wang L,Wang S,Li W,Liu Y,Zhang J
Mon Nov 01 00:00:00 UTC 2021
Inhibition of Growth of Colon Tumors and Proliferation of HT-29 Cells by Warburgia ugandensis Extract through Mediating G0/G1 Cell Cycle Arrest, Cell Apoptosis, and Intracellular ROS Generation.
Oxidative medicine and cellular longevity
Zhang Y,Chen G,Zhuang X,Guo M
Fri Mar 04 00:00:00 UTC 2022
Oxidative stress-induced mitophagy is suppressed by the miR-106b-93-25 cluster in a protective manner.
Cell death & disease
Zhang C,Nie P,Zhou C,Hu Y,Duan S,Gu M,Jiang D,Wang Y,Deng Z,Chen J,Chen S,Wang L
Wed Feb 24 00:00:00 UTC 2021
Liraglutide Protects Nucleus Pulposus Cells Against High-Glucose Induced Apoptosis by Activating PI3K/Akt/ mTOR/Caspase-3 and PI3K/Akt/GSK3β/Caspase-3 Signaling Pathways.
Frontiers in medicine
Yao M,Zhang J,Li Z,Bai X,Ma J,Li Y
Wed Mar 10 00:00:00 UTC 2021
Hsp47 Inhibitor Col003 Attenuates Collagen-Induced Platelet Activation and Cerebral Ischemic-Reperfusion Injury in Rats.
Frontiers in pharmacology
Wu S,Liang C,Xie X,Huang H,Fu J,Wang C,Su Z,Wang Y,Qu X,Li J,Liu J
Fri Jan 28 00:00:00 UTC 2022
Interaction of FLNA and ANXA2 promotes gefitinib resistance by activating the Wnt pathway in non-small-cell lung cancer.
Molecular and cellular biochemistry
Cheng L,Tong Q
Fri Oct 01 00:00:00 UTC 2021
Sulfiredoxin-1 protects retinal ganglion cells from high glucose-induced oxidative stress and inflammatory injury by potentiating Nrf2 signaling via the Akt/GSK-3β pathway.
International immunopharmacology
Zhu F,Shao J,Tian Y,Xu Z
Wed Dec 01 00:00:00 UTC 2021
Heme Oxygenase-1 Suppresses Wnt Signaling Pathway in Nonalcoholic Steatohepatitis-Related Liver Fibrosis.
BioMed research international
Du J,Ren W,Zhang Q,Fu N,Han F,Cui P,Li W,Kong L,Zhao S,Wang R,Zhang Y,Yang L,Kong L,Nan Y
Fri Mar 12 00:00:00 UTC 2021
Si-Miao-Yong-An Decoction attenuates isoprenaline-induced myocardial fibrosis in AMPK-driven Akt/mTOR and TGF-β/SMAD3 pathways.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhao Y,Sun D,Chen Y,Zhan K,Meng Q,Zhang X,Zhu L,Yao X
Thu Oct 01 00:00:00 UTC 2020
Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway.
Journal of cellular biochemistry
Li X,Meng Y,Xie C,Zhu J,Wang X,Li Y,Geng S,Wu J,Zhong C,Li M
Tue May 01 00:00:00 UTC 2018