Invitrogen

Phospho-GluR1 (Ser831) Polyclonal Antibody

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Phospho-GluR1 (Ser831) Antibody — Published figure using Phospho-GluR1 (Ser831) polyclonal antibody (Product # 36-8200)

Phospho-GluR1 (Ser831) Antibody in Western Blot (WB) — Western blot analysis of Phospho-GluR1 pSer831 in rat brain lysate using a Phospho-GluR1 pSer831 polyclonal antibody (Product # 36-8200).

Product Details

Tested Applications

Dilution

Western Blot (WB)

1:1000

Published Applications

Immunohistochemistry - Free Floating (IHC (Free))

See 1 publication below

Western Blot (WB)

See 1 publication below

Product Specifications

Species Reactivity

Rat

Published species

Not Applicable

Host / Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic phospho-peptide derived from the rat GluR1 protein.

Conjugate

Unconjugated

Form

Liquid

Purification

Antigen affinity chromatography

Storage buffer

0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

Contains

no preservative

Storage conditions

-20°C

RRID

AB_2533279

Target Information

GluR1 (glutamate receptor 1) is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter, L-glutamate, induces a conformation change that leads to the opening of the cation channel and converts the chemical signal to an electrical impulse. Then, the receptor desensitizes rapidly and enters a transiet inactive state characterized by the presence of a bound agonist. In the presence of CACNG4, CACNG7, or CACNG8 GluR1 shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: AMPA 1; AMPA-selective glutamate receptor 1; GluA1; GLUH1; GluR-1; GluR-A; GluR-K1; GLUR1; GLURA; glutamate receptor; Glutamate receptor 1; glutamate receptor A; Glutamate receptor ionotropic; Glutamate receptor ionotropic, AMPA 1; glutamate receptor subunit GluR1; glutamate receptor, ionotropic, AMPA1 (alpha 1); GRIA1; HBGR1; ionotropic; MGC133252

Gene Aliases: GluA1; gluR-A; Glur1; Gria1

UniProt ID: (Rat) P19490

Entrez Gene ID: (Rat) 50592

Molecular Function: ion channel ionotropic glutamate receptor ligand-gated ion channel receptor transporter