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Invitrogen

Phospho-HIPK2 (Tyr361) Polyclonal Antibody

4 Published Figures
4 References
View all (4) HIPK2 antibodies
635D49A6-4B57-425E-8DC4-6BA1AEB7B473 Created with sketchtool. Datasheet
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Product Details

Tested Applications
Dilution
Dot blot (DB)
1:500
Published Applications
Western Blot (WB)
See 3 publications below
Immunoprecipitation (IP)
See 1 publication below
Product Specifications
Species Reactivity
Human
Published species
Human
Host / Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y361 of human HIPK2
Conjugate
Unconjugated
Form
Liquid
Concentration
Lot-specific
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_10987115

Product Specific Information

This antibody is predicted to react with mouse and rat based on sequence homology.

Target Information

HIPK2 is a conserved serine/threonine nuclear kinase that interacts with homeodomain transcription factors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: hHIPk2; Homeodomain-interacting protein kinase 2

Gene Aliases: HIPK2; PRO0593

UniProt ID: (Human) Q9H2X6

Entrez Gene ID: (Human) 28996

Molecular Function: kinase non-receptor serine/threonine protein kinase non-receptor tyrosine protein kinase protein kinase transferase

Function(s)
negative regulation of transcription from RNA polymerase II promoter eye development transcription, DNA-templated protein phosphorylation DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator transforming growth factor beta receptor signaling pathway smoothened signaling pathway adult walking behavior positive regulation of cell proliferation anterior/posterior pattern specification retina layer formation peptidyl-serine phosphorylation peptidyl-threonine phosphorylation modulation by virus of host morphology or physiology neuron differentiation erythrocyte differentiation positive regulation of transforming growth factor beta receptor signaling pathway negative regulation of BMP signaling pathway PML body organization positive regulation of protein binding intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator positive regulation of DNA binding negative regulation of neuron apoptotic process positive regulation of angiogenesis positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of JNK cascade embryonic camera-type eye morphogenesis voluntary musculoskeletal movement positive regulation of sequence-specific DNA binding transcription factor activity regulation of cell cycle embryonic retina morphogenesis in camera-type eye lens induction in camera-type eye SMAD protein signal transduction iris morphogenesis cellular response to hypoxia intrinsic apoptotic signaling pathway regulation of signal transduction by p53 class mediator
Process(es)
RNA polymerase II activating transcription factor binding RNA polymerase II transcription coactivator activity transcription corepressor activity protein kinase activity protein serine/threonine kinase activity protein binding ATP binding SMAD binding virion binding

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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