|Western Blot (WB)||1:1000|
|Tested Species reactivity||Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic phospho-peptide corresponding to amino acid residues surrounding Tyr1325 of rat GRIN2A conjugated to KLH|
|Storage buffer||0.01M HEPES, pH 7.5, with 0.1mg/ml BSA, 50% glycerol, 0.15M NaCl|
This antibody contains enough material to conduct 10 mini-Western blots.
The NMDA Receptor (NMDAR) plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death. The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS. The NMDAR is also potentiated by protein phosphorylation. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of th NMDAR2 (NR2 A-D) subunits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GluN2A; GluRepsilon1; Glutamate [NMDA] receptor subunit epsilon-1; Glutamate NMDA receptor subunit epsilon-1; Glutamate receptor ionotropic NMDA 2A; Glutamate receptor ionotropic, NMDA 2A; Grin2a; N-methyl D-aspartate receptor subtype 2A; N-methyl-D-aspartate receptor subunit 2A; N-Methyl-D-Aspartate Receptor Type 2A; NMDAR2A; NR2A
Gene Aliases: GluN2A; Grin2a; NMDAR2A; NR2A
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