Invitrogen

RAB17 Monoclonal Antibody (OTI5E2)

Product Image Gallery

RAB17 Antibody in Immunocytochemistry (ICC) — Immunofluorescent analysis of RAB17 in COS7 cells. Cells were transfected with a plasmid overexpressing RAB17 and probed with a RAB17 monoclonal antibody (Product # MA5-25117).

RAB17 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry was performed on paraffin-embedded carcinoma of human liver tissue. To expose target proteins, 10mM citric buffer, pH6.0, 100°C for 10min was used. Following antigen retrieval, tissues were probed with a RAB17 monoclonal antibody (Product # MA5-25117) at a dilution of 1:50.

RAB17 Antibody in Western Blot (WB) — Western blot analysis of RAB17 in HEK293T cells in untransfected (Left lane) and transfected (Right lane) samples using 5 µg per lane. The samples were separated by SDS-PAGE and probed with RAB17 (Product # MA5-25117) monoclonal antibody.

Product Details

Tested Applications

Dilution

Immunocytochemistry (ICC)

1:100

Immunofluorescence (IF)

1:100

Immunohistochemistry (Paraffin) (IHC (P))

1:50

Western Blot (WB)

1:2000

Product Specifications

Species Reactivity

Human

Host / Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI5E2

Immunogen

Full length human recombinant protein of RAB17 produced in HEK293T cell

Conjugate

Unconjugated

Form

Liquid

Concentration

0.63 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

RRID

AB_2725168

Target Information

The Rab subfamily of small GTPases plays an important role in the regulation of membrane trafficking. RAB17 is an epithelial cell-specific GTPase (Lutcke et al., 1993 [PubMed 8486736]).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: AW413472; RAB17; RAB17, member RAS oncogene family; Ras-related protein Rab-17

Gene Aliases: RAB17

UniProt ID: (Human) Q9H0T7

Entrez Gene ID: (Human) 64284

Function(s)

immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor small GTPase mediated signal transduction protein transport regulation of endocytosis establishment of melanosome localization melanosome transport endocytic recycling cilium assembly transcytosis filopodium assembly regulation of dendrite development regulation of filopodium assembly regulation of synapse assembly

Process(es)

GTPase activity protein binding GTP binding GDP binding

RAB17 Monoclonal Antibody (OTI5E2)

Product Details

Target Information

Bioinformatics

Material safety data sheets (MSDS)

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