This Antibody was verified by KnockDown to ensure that the antibody binds to the antigen stated. View Details
MA1-23269 detects Rad50 in human samples.
MA1-23269 has been successfully used in immunofluorescence, immunohistochemistry, immunoprecipitation and Western blot procedures.
MA1-23269 immunogen is residues 1-425 of Rad50 expressed in E. coli..
Rad50-13B3 recognizes human Rad50, a 153a protein involved in DNA double strand break repair. Rad50 is associated with Mre11 and p95 (Nibrin) to form a multiprotein complex involved in the double strand break repair process. Upon DNA damage, Rad50 and Mre11 redistribute and are co-localized within the nucleus of damaged cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DNA repair protein RAD50; hRAD50; mRad50; NBSLD; RAD50 homolog, double strand break repair protein; RAD50-2
Gene Aliases: hRad50; Mrell; NBSLD; RAD50; RAD502; Rad50l