|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Recombinant protein derived from the C-terminal region of the human RCAS1|
|Storage buffer||tissue culture supernatant|
|Contains||0.1% sodium azide|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Immunohistochemistry (IHC)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
RCAS1 (Receptor binding cancer antigen expressed on SiSo cells, Estrogen receptor-binding fragment-associated gene 9 protein, BAG9) is a type III transmembrane protein that is predominantly located in the Golgi. It induces apoptosis of natural killer (NK)/T cells and plays a role in immune invasion, possibly in relation to Epstein-Bar virus infection. RCAS1 is abundantly expressed in prostate cancer cells when compared to normal epithelial cells, and immunodetection of RCAS1 expression can be a negative prognostic indicator for patients with prostate cancer
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.