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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Chicken / IgY|
|Immunogen||Synthetic peptide corresponding to residues 41-100 of RGS17.|
|Purification||Antigen affinity chromatography|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:2,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-25695 detects RGS17 / RGSZ2 from human, mouse, and rat samples.
PA1-25695 has been successfully used in Western blot procedures. It has a predicted molecular weight of 25 kDa.
The PA1-25695 immunogen is a synthetic peptide corresponding to residues 41-100 of RGS17.
Store at 4°C short term. For extended storage, store at -20°C, avoiding freeze/thaw cycles.
This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
hRGS17; regulator of G-protein signaling 17; regulator of G-protein signaling Z2; regulator of Gz-selective protein signaling 2; RGS-17; RGSZ2
6430507P11Rik; hRGS17; RGS-17; RGS17; RGSZ2