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Immunogen sequence: VIRPGFQRA CVAAACTVAA RCPGRGVGDR SQSGASYRPI CGPKVGGPTE MLRGMYLTRN GNLQRRHTMK EAKDMKNKLG IFRRRSESPG APPAGKADKM MKSFKPTSEE ALKWGESLEK LLVHKYGLAV FQAFLRTEFS EENLEFWLAC EDFKKVKSQS KMASKAKKIF AEYIAIQACK EVNLDSYTRE HTKDNLQSVT RGCFDLAQKR IFGLMEKDSY PRFLRSDLYL DLINQKKMSP PL (1-241 aa encoded by BC018072)
This gene encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTP-ase activating protein which inhibits G-protein mediated signal transduction. The protein is largely cytosolic, but G-protein activation leads to translocation of this protein to the plasma membrane. A nuclear form of this protein has also been described, but its sequence has not been identified. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature of some transcripts is not yet known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ20370; FLJ31516; FLJ90496; Regulator of G-protein signaling 3; regulator of G-protein signalling 3; RGP3
Gene Aliases: C2PA; RGP3; RGS3
UniProt ID: (Human) P49796
Entrez Gene ID: (Human) 5998
Molecular Function: GTPase-activating protein
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