The protein encoded by this gene is an isozyme of very long-chain acyl-CoA synthetase (VLCS). It is capable of activating very long-chain fatty-acids containing 24- and 26-carbons. It is expressed in liver and associated with endoplasmic reticulum but not with peroxisomes. Its primary role is in fatty acid elongation or complex lipid synthesis rather than in degradation. This gene has a mouse ortholog.
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Protein Aliases: ACSB; ACSVL6; BA-CoA ligase; BACS; BAL; Bile acid-CoA ligase; Bile acyl-CoA synthetase; Cholate--CoA ligase; FACVL3; FATP-5; FATP5; Fatty acid transport protein 5; Fatty-acid-coenzyme A ligase, very long-chain 3; solute carrier family 27 (fatty acid transporter), member 5; Solute carrier family 27 member 5; Very long-chain acyl-CoA synthetase homolog 2; Very long-chain acyl-CoA synthetase-related protein; very long-chain acyl-Coenzyme A dehydrogenase synthase related; VLACS-related; VLACSR; VLCS-H2; VLCSH2
Gene Aliases: ACSB; ACSVL6; BACS; BAL; FACVL3; FATP-5; FATP5; SLC27A5; VLACSR; VLCS-H2; VLCSH2
Molecular Function: ligase