This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: PLATSTDHGH NLQTVQLLIK KNQTLQKEIQ GHQPRIDDIF ERSQNIVTDS SSLSAEAIRQ RLADLKQLWG LLIEETEKRH RRLEEAHRAQ QYYFDAAEAE AWMSEQEL
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.
Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: a--fodrin; alpha II spectrin; alpha-fodrin; Alpha-II spectrin; alpha-spectrin 2; beta fodrin; beta-fodrin; beta-G spectrin; Beta-II spectrin; beta-spectrin 2; beta-spectrin 2, non-erythrocytic; beta-spectrin II; beta-spectrin non-erythrocytic 1; brain alpha-spectrin; brain spectrin; embryonic liver beta-fodrin; Embryonic liver fodrin; epididymis luminal protein 102; Fodrin alpha chain; Fodrin beta chain; inhibitory protein factor; noerythroid alpha-spectrin 2; non-erythrocytic; nonerythroid alpha-spectrin 2; spectrin alpha chain, brain; Spectrin alpha chain, non-erythrocytic 1; spectrin beta 2; spectrin beta chain, brain 1; Spectrin beta chain, non-erythrocytic 1; spectrin G; spectrin, beta, non-erythrocytic 1; spectrin, non-erythroid alpha chain; Spectrin, non-erythroid beta chain 1
Gene Aliases: 9930031C03Rik; A2a; AL033301; betaSpII; ELF; elf1; elf3; HEL102; IPF; mKIAA4049; Spna2; Spnb-2; Spnb2; Spta2; Sptan1; SPTB2; SPTBN1